The Beluga retains the same modern flight deck that is in worldwide operation on Airbus A300-600s and A310s.

It is operated by a three-member crew comprising two pilots and a loadmaster. The main instrument panel incorporates six cathode ray tube (CRT) displays that continuously provide flight, navigation and systems-monitoring information in a clear, comprehensive manner.

Also included in the cockpit are controls for a transportable heating module that can be installed in the main deck cargo compartment. The module provides temperature-controlled conditions for sensitive payloads carried by the Beluga, including satellites and paintings.