Operated by airlines on all five continents, the A300 and A310 have earned their reputation as "regional profit machines" with an unmatched combination of versatility, economy and reliability.

The A300-600 is the benchmark for operating economy in its size category, with direct operating costs per seat (including ownership costs) up to 9 per cent lower than those of the nearest competitor. A major advantage is its profitability at the upper end of the mid-size jetliner category. With up to 28 more seats than its nearest competitor and offering more practical use of the underfloor hold volume, the A300-600 has substantially greater revenue-generating potential. With the same passenger load factor, one A300-600 makes $1.4 million (U.S.) more profit per year than its competitor.

The A310 has lower operating weights and requires lower thrust levels than competing aircraft. As a result, the A310’s direct operating costs per seat are up to 10 per cent lower. The optimised 222-inch fuselage cross-section used for both the A300 and A310 allows significant amounts of revenue-generating freight to be carried in the lower deck holds, including freight pallets and industry-standard LD3 containers.